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Zhiyuan has successfully developed super water-soluble fluorfenicol inclusion complex

Pharmacodynamics Flumfenicol belongs to amido alcohols and has strong antibacterial activity against a variety of gram-positive bacteria, gram-negative bacteria and mycoplasma. Flufenicol is primarily a bacteriostatic agent that inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome.In vitro, the antibacterial activity of florfenicol against many microorganisms is similar to or stronger than that of chloramphenicol and dacamphenicol. Some bacteria resistant to chloramphenicol due to acetylation, such as Escherichia coli and Klebsiella pneumoniae, may still be sensitive to florfenicol.

Zhiyuan’s water-soluble fluorfenicol inclusion complex is 10% fluorfenicol high water-soluble powder, the solubility of inclusion complex is greater than 35%, and the concentration of fluorfenicol can reach more than 50000ppm, which is more than 10 times the concentration of fluorfenicol dissolution on the market at present.The water is completely dissolved and there is no sediment.Adopts special process to pack fluorfenicol raw materials, organic carrier, its solid dispersion technology has reached the molecular level, the dispersion and both were once the leading level in China, good solubility, long time standing will not precipitate, higher bioavailability, better antibacterial effect.

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