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Hydroxypropyl Betadex

DMF No. : 030168, Cas No.128446-35-5, pharmaceutical grade Hydroxypropyl Betadex. The introduction of hydroxypropyl group breaks the intramolecular annular hydrogen bond of beta-cyclodextrin, which overcomes the main shortcoming of poor water-solubility of beta-cyclodextrin while maintaining the cavity of beta-cyclodextrin.

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Product Description

Hydroxypropyl Betadex Pharmaceutical Grade

 

Product Name

Hydroxypropyl Betadex

CAS No.

128446-35-5

Other Names

hpbcd,HPBCD

Appearance

White powder, sweet, insipid innocent.

Molecular Formula 

C42H70-nO35(C3H8O2)n

Molecular Weight 

1134.98+58n

Standard

CP, USP, EP

Solubility

≥100(25℃,g/100ml)

 

Description: 
Hydroxypropyl betadex is a hydroxylated derivative of beta-cyclodextrin, is non-toxic and has no side effects. Due to the particularity of its structure, it can greatly improve the solubility of insoluble drugs and make insoluble or insoluble drugs dissolve in water.


Characteristics & Applications:

Hydroxypropyl betadex (HP-β-CD, hpbcd) is a hydroxylated derivative of beta-cyclodextrin (β-CD). Hydroxypropyl betadex is non-toxic and has no side effects. Due to the particularity of its structure, it can greatly improve the solubility of insoluble drugs and make insoluble or insoluble drugs dissolve in water. It is an ideal solvent enhancer and drug excipient for injection. Its main functions in the field of medicine are as follows:

(1) Solubilize and assist the solubility of insoluble drugs, improve the solubility of active ingredients of oil drugs, target drug delivery and protect the effectiveness of drug ingredients.

(2) Improve the bioavailability of drugs to increase the efficacy or reduce the dosage of drugs.

(3) Adjust or control the release rate of drugs to reduce the toxic and side effects of drugs.

(4) cover up bad smell.

 

Pharmaceutical grade hydroxypropyl betadex can be used in oral drugs, injections, mucosal drug delivery system (including nasal mucosa, rectum, cornea, etc.), transdermal absorption drug delivery system, carrier of lipopilic targeted drugs, and can also be used as a protein protectant and stabilizer.

 

 

Speciafication:

Please find attached TDS.

 

Packaging:

Normal package: 10kg/fiber drum, 20kg/fiber drum or customized. Packed in clean workshop.

 

Storage:

Preserve in well-closed containers. Store at room temperature.

 

FAQ:

1. What's the main advantanges about your factory?
We have a professional product research and development team, the most advanced production line and detecting instruments, sales team with humanistic service (including after-sale service). Conforms to GMP standand and meets USP, EP.

 

2. How can you ensure the quality you provided ?

We have established a complete procedure to check products at all stages of the manufacturing process-raw materials, process materials, validated or tested materials finished goods etc.. And we have developed a procedure to identify the inspection and test status of all stages of the manufacturing process. We also keep samples for at least 2 years and keep doing stability test.

 

3. Can purchaser come to audit?
We warmly welcome customers' audit, it's an effective way to build a better business relationship.


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