Water-soluble menthol inclusion complex
Appearance: white powder
|Test Standard||Enterprise Standard|
|Appearance||White powder, unique smell|
|Content of Menthol||≥7.7%|
|Water solution pH||5.5~7.2|
|Solubility in water (25℃)||≥55.1%|
|Loss on Drying||≤6%|
|The total aerobic microbial count||≤1000cfu/g|
|The total combined moulds and yeastscount||≤100cfu/g|
|Packaging and storage||Preserve in well-closed containers.|
The solubilization of menthol by HP-beta-CD inclusion significantly increased the solubility of menthol in water, which was conducive to its preparation in aqueous solution.
It has the following characteristics:
(1)Increasing the water solubility of menthol and reducing its volatilization;
(2)Using water dosage form to avoid side effects such as ethanol allergy;
(3)Making the injection safer, less toxic side effects, overcoming edema or tissue necrosis, and making wound healing faster;
(4)Analgesia time can be adjusted for 4-8 days according to need;
(5)Dosage form can be diversified according to demand.
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